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Promethazine might reduced seizure threshold. It ought to be used with warning in folks with seizure Conditions or in individuals that are using concomitant medicines, such as narcotics or neighborhood anesthetics, which may also have an affect on seizure threshold.
If you're thinking that there has been an overdose, phone your poison Command Middle or get professional medical care immediately. Be ready to tell or display what was taken, the amount of, and when it took place. How do I keep and/or toss out Promethazine and Codeine?
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This immediate conversion brings about bigger than envisioned serum morphine ranges. Even at labeled website dosage regimens, individuals who are extremely-immediate metabolizers may perhaps experience overdose signs and symptoms such as extreme sleepiness, confusion, or shallow respiratory.
Virtually all research examining the usage of promethazine in pregnancy didn't locate an Affiliation with an increased possibility of congenital anomalies. While in the couple of experiments reporting an association, no regular sample of malformations website was mentioned.
Constantly use an exact milliliter measuring gadget when administering Promethazine with Codeine Oral Option to make certain that the dose is calculated and administered accurately. A house teaspoon is not really an accurate measuring unit and may lead to overdosage [see Warnings and click here Safety measures ( 5.7)]. For prescriptions in which a measuring product is not check here really supplied, a pharmacist can offer an appropriate measuring product and can offer Guidance for measuring the proper dose. Do not overfill.
It's soluble in h2o and freely soluble in Liquor. It's a molecular weight of 320.88, a molecular method of C17H20N2S•HCI, and the subsequent structural formula:
Codeine may possibly impair your imagining or reactions. Stay clear of driving or operating machinery until you know how this drugs will have an affect on you. Dizziness or severe drowsiness can cause falls or other incidents.
The combination of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric individuals below 6 many years of age, simply because the combination may perhaps induce deadly respiratory depression With this age inhabitants.
If you utilize this drugs if you are pregnant, your infant could turn into depending on the drug. This could potentially cause life-threatening withdrawal signs in the infant soon after it's born.